Castaño G, Mas R, Fernández L et al: Assessment of the effects of D-003, a new antiplatelet and hypocholesterolemic compound on healthy volunteers: a Phase I Clinical Study. Drugs R&D 2002; 23:193-203.
Arruzazabala ML, Carbajal D, Mas R et al: Effects of D-003, a new compound purified from sugar cane wax, on platelet aggregation in healthy volunteers: A randomized, double-blinded clinical study. Clin Drug Invest 2002; 23:107-118.
Castaño, G, Menéndez R, Mas R et al: Effects of D-003 on lipid profile and lipid peroxidation in healthy volunteers Clin Drug Invest 2003; 23:193-203.
Pérez Y, Menéndez R, Mas R, González RM, Fernández L, Fernández JC, Illnait J, Mendoza S. Effects of D-003, a mixture of high molecular weight acids from sugarcane wax, on lipid peroxidation (LP) markers of older individuals. Curr Ther Res 2008; 69:36-48.
Arruzazabala ML, Molina V, Carbajal D, et al. Effects of D-003, a mixture of very long chain fatty acids purified from sugar cane wax, at 5 and 10 mg/d on platelet aggregation in healthy volunteers Int J Phamacol Clin Res 2005; 25:29- 39.
Arruzazabala ML, Molina V, Carbajal D et al. Effects of D-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. Int J Pharmacol Clin Res 2004; XXIV:56-64.
Castaño G, Mas R, Fernández L et al. Effects of D-003 (5 – 40 mg/day) on lipid profile of patients with Type II hypercholesterolemia: a Phase II clinical study. Clin Drug Invest 2003; 23:789-802.
Castaño G, Mas R, Fernández L, et al. A comparison of the effects of D-003 and policosanol (5 and 10 mg/d) in patients with Type II hypercholesterolemia: a randomized, double-blinded study. Drugs Exptl Clin Res 2005, XXX (Suppl), 31-44.
Arruzazabala ML, Molina V, López E, Castaño G, Fernández L, Carbajal D, Mas R, Illnait J, Mendoza S, Ramírez Y. Effects of D-003, a mixture of sugarcane wax acids, on platelet aggregation in hypercholesterolemic patients: a dose-titration, randomised, placebo-controlled trial. Arzn- Forsch Drug Res 2008; 58: 376-384.
Castaño G, Mas R, Fernández L et al. Efectos del D-003 (5 - 20 mg/día) sobre el perfil lipídico en pacientes con hipercolesterolemia (HC) tipo II: Un estudio de “titulación de la dosis” (Datos del registro).
Castaño G, López E, Mas R et al. efectos a largo plazo (1 año) del D-003 y el policosanol (5 - 20 mg/d) sobre el perfil lipídico en pacientes con hipercolesterolemia (HC) Tipo II (Datos del registro).ç
Pérez P, Illnait J, Fernández L, Mesa M, Fernández JC, Gámez R, Mas R, Gómez M, Jardines Y, Ruiz D. Effects of D-003 (sugar cane alcohols) on the physical exercise on the static bicycle test. LAJP 2010; 29:263-70.
Arruzazabala ML, López E, Molina V, Illnait J, Carbajal D, Mas R, Fernández L, Fernández JC, Gámez R, Ravelo Y, Mesa M, Mendoza S, Ruiz D, Jardines Y. Efectos del D-003, una mezcla de ácidos grados de la caña de azúcar, sobre el perfil lipídico y la agregación plaquetaria de pacientes con diabetes tipo 2. Un ensayo controlado con placebo. Acta Bioquímica Clín Latinoam 2010; 44: 15-24.
Ceballos A., Mas R., Castaño G., et al. The effect of D-003 (10 mg/day) on biochemical parameters of bone remodelling in postmenopausal women: a randomized, double-blind study. Int J Clin Pharmacol Res 2005; 25:175-186.
Ceballos A, Mas R., Castaño G., Fernández L., Mendoza S., Menéndez R., González J.J., Illnait J., Gámez R., Mesa M, Fernández J. The effect of D-003 (10 mg/day) on biochemical paramaters of bone remodelling in postmenopausal women: a randomized double-blind study. Int J Clin Pharm Res 25:175-186.
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