Section to complete information about primary and secondary outcomes including. It includes the metric or method of measurement used and, the time point for every outcome.
Primary outcome(s):
Postoperative analgesia (Pain intensity using a Visual Analog Scale). Measurement time: 1 hour (h), 2h , 3h, 4h, 12h, 24h, 48h and 72h after the extubation of the patient. Total doses of morphine used in the postoperative period (mg).Measurement time: At leave to the postoperative intensive care unit. Time to extubation (Hours between the end of the surgery and the extubation of the patient).
Key secondary outcomes:
Intraoperative analgesia (Hemodynamic changes in mean arterial blood pressure and heart rate during the incision of the skin, sternotomy and pericardiotomy). Measurement time: At the end of surgery Total doses of fentanyl used in the period (in micrograms). Measurement time: At the end of surgery. Adverse Events related to Opioid treatment (Yes/No). Measurement time: every 24 hour until hospital discharge. Perioperative complications (Yes/No). Measurement time: each 24 hour until hospital discharge. Complications associated with the use of regional anesthesia (Yes/No). Measurement time: every 24 hour until hospital discharge. Cost in the Intensive Care Unit (ICU). Measurement time: At leave the ICU ICU cost per day: Cost of a bed day per patient in ICU. Value used by the Economic department of the clinical site, 700 CUC per day). Cost in the hospital stay (including the days between ICU dischage until hospital discharge). Measurement time: At hospital discharge. The hospital stay cost per day: cost per day per patient from a bed in room. Value used by the Economic department of the clinical site, 350 CUC per day).